Beaten play-off finalists Bristol Manor Farm start at home to Melksham Town in Pitching In Southern Division One South.
Lee Lashenko’s side finished fourth last term, 12 places above Melksham.
Farm beat Cribbs in the play-off semi-finals. Their new-look side start at Cinderford on August 10, who won promotion back to Step 4 after success in the Hellenic League play-offs.
Larkhall Athletic just missed out on the top five last term. They are at Didcot Town on August 10, who are the only side relegated to this division.
Cornish duo Falmouth Town and Helston Athletic both open with long journeys to Bashley and Westbury United respectively. Evesham United make the near 500-mile round trip to Mousehole on day one.
Shaftesbury’s first game at this level is home to Malvern Town while Thatcham Town, transferred from the Isthmian League, head to Devon on the opening day where Exmouth Town are the hosts.
Two other games in that county see Tavistock play Yate Town and Willand Rovers take on Bemerton Heath Harlequins, while Devonians Bideford start at Bishops Cleeve.
Opening day fixtures in full:
Bashley vs Falmouth Town
Bishops Cleeve vs Bideford
Bristol Manor Farm vs Melksham Town
Cinderford Town vs Cribbs
Didcot Town vs Larkhall Athletic
Exmouth Town vs Thatcham Town
Mousehole vs Evesham United
Shaftesbury vs Malvern Town
Tavistock vs Yate Town
Westbury United vs Helston Athletic
Willand Rovers vs Bemerton Heath Harlequins
