Real Bedford face Hertford Town in their first Southern League Central contest on August 10.
Rob Sinclair’s side have won back-to-back promotions with bitcoin podcaster Peter McCormack as chairman.
The two other promoted sides, Flackwell Heath and Leverstock Green, also start at home against AFC Dunstable and Welwyn Garden City respectively.
Berkhamsted’s first game following relegation sees them host Stotfold while Beaconsfield Town, who also lost their Step 3 status last year, begin at Northwood.
Enfield have moved laterally from Isthmian North and start at home to North Leigh.
Reprieved Thame United open away to Ware.
The league win run with 21 teams after Coalville Town’s resignation from Step 3 reprieved Hitchin Town. Leighton Town are without a game on the opening day, they open at home to Biggleswade on Tuesday August 13.
Biggleswade’s opening game is home to Aylesbury United with Kidlington hosting Kings Langley in the division’s other match on the Saturday.
Opening day fixtures in full:
Berkhamsted vs Stotfold
Biggleswade FC vs Aylesbury United
Enfield FC vs North Leigh
Flackwell Heath vs AFC Dunstable
Hadley vs Barton Rovers
Kidlington vs Kings Langley
Leverstock Green vs Welwyn Garden City
Northwood vs Beaconsfield Town
Real Bedford vs Hertford Town
Ware vs Thame United
